Istanbul Airport Airlines
| Airlines | Destinations |
|---|---|
| Aegean Airlines | Athens |
| Aeroflot | Moscow–Sheremetyevo |
| Afriqiyah Airways | Bayda, Tripoli–Mitiga |
| Air Albania | Tirana |
| Air Algérie | Algiers, Annaba, Constantine, Oran |
| Air Astana | Almaty, Atyrau, Nur-Sultan |
| Air France | Paris–Charles de Gaulle |
| Air Moldova | Chişinău |
| Air Serbia | Belgrade |
| All Nippon Airways | Tokyo–Haneda |
| Ariana Afghan Airlines | Kabul (suspended), Mazar-i-Sharif (suspended) |
| Asiana Airlines | Seoul–Incheon |
| Avia Traffic Company | Bishkek |
| Azerbaijan Airlines | Baku |
| Badr Airlines | Khartoum |
| Belavia | Minsk |
| British Airways | London–Heathrow |
| Buraq Air | Tripoli–Mitiga |
| China Southern Airlines | Beijing–Daxing, Wuhan |
| Corendon Airlines | Casablanca |
| EgyptAir | Cairo |
| Emirates | Dubai–International |
| Ethiopian Airlines | Addis Ababa |
| Etihad Airways | Abu Dhabi |
| Fly Baghdad | Baghdad, Erbil |
| Gulf Air | Bahrain |
| HiSky | Chișinău |
| IndiGo | Delhi |
| Iran Air | Tehran–Imam Khomeini |
| Iran Air Tours | Isfahan,Mashhad,Shiraz,Tabriz,Tehran–Imam Khomeini |
| Iran Aseman Airlines | Tehran–Imam Khomeini |
| Iraqi Airways | Baghdad, Basra, Erbil, Sulaimaniyah |
| Jazeera Airways | Kuwait |
| Jordan Aviation | Amman–Queen Alia |
| Kam Air | Kabul (suspended) |
| KLM | Amsterdam airport |
| Korean Air | Seoul–Incheon |
| Kuwait Airways | Kuwait |
| LOT Polish Airlines | Warsaw–Chopin |
| Lufthansa | Frankfurt |
| Libyan Airlines | Bayda, Tripoli–Mitiga |
| Libyan Wings | Tripoli–Mitiga |
| Mahan Air | Tehran–Imam Khomeini |
| Meraj Airlines | Mashhad, Tehran–Imam Khomeini |
| Middle East Airlines | Beirut |
| Nordwind Airlines[45] | Kaliningrad, Kazan, Moscow–Sheremetyevo,Rostov-on-Don, Saint Petersburg, Samara |
| Nouvelair | Tunis |
| Oman Air | Muscat |
| Onur Air | Kuwait |
| Pegasus Airlines | Izmir,Tehran–Imam Khomeini |
| Pobeda | Kazan, Mineralnye Vody, Moscow–Sheremetyevo, Moscow–Vnukovo, Ufa, Yekaterinburg |
| Qatar Airways | Doha |
| Qeshm Air | Tehran–Imam Khomeini |
| Red Wings Airlines | Kazan, Moscow–Domodedovo, Rostov-on-Don, Saint Petersburg, Ufa, Yekaterinburg |
| Rossiya Airlines | Saint Petersburg |
| Royal Air Maroc | Casablanca |
| Royal Jordanian | Amman–Queen Alia |
| Saudia | Jeddah, Medina, Riyadh |
| SCAT Airlines | Aktau, Shymkent |
| Sichuan Airlines | Chengdu–Shuangliu |
| Singapore Airlines | Singapore |
| SkyUp | Kyiv–Boryspil, Lviv, Odessa Seasonal: Kharkiv, Zaporizhzhia |
| Somon Air | Dushanbe |
| TAROM | Bucharest |
| Transavia | Nantes |
| Tunisair | Tunis |
| Turkish Airlines | Abidjan, Abu Dhabi, Abuja, Accra, Adana, Addis Ababa, Adıyaman, Ağrı, Aktau, Alexandria, Algiers, Almaty, Amman–Queen Alia, Amsterdam, Ankara, Antalya, Antananarivo, Aqaba, Ashgabat, Asmara, Athens, Atlanta, Baghdad, Bahrain, Baku, Bamako, Bangkok–Suvarnabhumi, Banjul, Barcelona, Bari, Basel/Mulhouse, Basra, Batman, Batumi, Beijing–Capital, Beirut, Belgrade, Berlin, Bilbao, Billund, Bingöl, Birmingham, Bishkek, Bodrum, Bogotá, Bologna, Bordeaux, Boston, Bremen, Brussels, Bucharest, Budapest, Buenos Aires–Ezeiza, Cairo, Çanakkale, Cancún, Cape Town, Caracas, Casablanca, Catania, Chicago–O’Hare, Chișinău, Cluj-Napoca, Cologne/Bonn, Colombo–Bandaranaike, Conakry, Constanța, Constantine, Copenhagen, Cotonou, Dakar–Diass, Dalaman, Dallas/Fort Worth (begins 24 September 2021), Dammam, Dar es Salaam, Delhi, Denizli, Denpasar/Bali, Dhaka, Diyarbakir, Djibouti, Doha, Douala, Dubai–International, Dublin, Dubrovnik, Durban, Dushanbe, Düsseldorf, Edinburgh, Edremit, Elazığ, Entebbe, Erbil, Erzincan, Erzurum, Frankfurt, Freetown, Ganja, Gassim, Gaziantep, Gazipaşa, Geneva, Gothenburg, Graz, Guangzhou, Hakkari, Hamburg, Hannover, Hanoi, Hatay, Havana, Helsinki, Ho Chi Minh City, Hong Kong, Houston–Intercontinental, Hurghada, Iğdır, Isfahan, Islamabad, İzmir, Jakarta–Soekarno-Hatta, Jeddah, Johannesburg–O. R. Tambo, Kabul (suspended), Kahramanmaraş, Karachi, Kars, Kastamonu, Kathmandu, Kayseri, Kazan, Kharkiv, Khartoum, Kherson, Kigali, Kilimanjaro, Kinshasa–N’djili, Konya, Krasnodar, Kuala Lumpur–International, Kütahya–Zafer, Kuwait, Kyiv–Boryspil, Lagos, Lahore, Lefkoşa-Ercan, Leipzig/Halle, Libreville, Lisbon airport, Ljubljana, London–Gatwick, London–Heathrow, Los Angeles, Luanda (begins 27 October 2021), Lusaka, Luxembourg, Luxor, Lviv, Lyon, Madrid, Mahé, Malabo, Málaga, Malatya, Malé, Malta, Manchester, Manila, Maputo, Mardin, Marrakech, Marseille, Mashhad, Mauritius, Mazar-i-Sharif (suspended), Medina, Merzifon, Mexico City, Miami, Milan–Malpensa, Minsk, Mogadishu, Mombasa, Montréal–Trudeau, Moscow–Vnukovo, Mumbai, Munich, Muş, Muscat, Mykolaiv (begins 23 September 2021), Nairobi–Jomo Kenyatta, Najaf, Nakhchivan, Naples, N’Djamena, Nevşehir, Newark, New York–JFK, Niamey, Nice, Nouakchott, Nuremberg, Nur-Sultan, Odessa, Oran, Ordu–Giresun, Osaka–Kansai,[54] Oslo, Ouagadougou, Panama City–Tocumen, Paris–Charles de Gaulle, Phuket, Podgorica, Pointe Noire, Port Harcourt, Porto, Port Sudan, Prague, Pristina, Riga, Riyadh, Rome–Fiumicino, Rostov-on-Don, Saint Petersburg, Salzburg, Samara, Samarkand, Samsun, San Francisco, Şanlıurfa, São Paulo–Guarulhos, Sarajevo, Seoul–Incheon, Shanghai–Pudong, Sharjah, Sharm El Sheikh, Shiraz, Singapore, Sinop, Şırnak, Sivas, Skopje, Sochi, Sofia, Stockholm–Arlanda, Strasbourg, Stuttgart, Sulaymaniyah, Tabriz, Ta’if, Taipei–Taoyuan, Tallinn, Tashkent, Tbilisi, Tehran–Imam Khomeini, Tel Aviv, Thessaloniki, Tokyo–Haneda, Tokyo–Narita, Toronto–Pearson, Toulouse, Trabzon, Tunis, Turkistan, Ufa, Ulaanbaatar, Urgench, Uşak, Valencia, Van, Vancouver, Varna, Venice, Vienna, Vilnius, Voronezh, Warsaw–Chopin, Washington–Dulles, Xi’an, Yanbu, Yaoundé, Yekaterinburg, Zagreb, Zanzibar, Zaporizhzhia, Zonguldak, Zürich Seasonal: Friedrichshafen, Moroni, Pisa, Rovaniemi |
| Turkmenistan Airlines | Ashgabat |
| Ukraine International Airlines | Kyiv–Boryspil, Odessa |
| Utair | Grozny |
| Uzbekistan Airways | Samarkand, Tashkent |